Breakthrough Discovery in Pancreatic Tumors Through Innovative Genomic Testing
A Journey Through Cancer: Connie Waxman’s Story
In a poignant journey of survival and resilience, Connie Waxman faced a daunting diagnosis of stage III pancreatic adenocarcinoma on January 28, 2014, at the age of 56. Initially attributing her back pain to a new exercise routine, Connie soon found herself battling a series of alarming symptoms that led her to seek medical advice. What followed was a roller coaster of treatments, expert opinions, and ultimately, hope.
Recognizing the Signs
Connie’s health concerns began with persistent back pain and stomach discomfort after meals. Despite trying to modify her exercise regimen, the symptoms did not subside. Losing weight over the holidays, a time typically associated with festive feasting, prompted her to consult her primary care physician. A CT scan revealed a worrying mass on her pancreas, leading to further tests that confirmed the tumor’s inoperable state due to its entanglement with the superior mesenteric artery.
Seeking Expert Opinions
Desperate for answers, Connie turned to the Cleveland Clinic but was met with grim news. The surgeon informed her that the tumor was deemed inoperable, and she might have less than a year to live. Undeterred, she sought a second opinion at Johns Hopkins, where she met with Dr. Daniel Laheru, a respected oncologist. Together, they devised a treatment plan involving chemotherapy and radiation, with the intent of shrinking the tumor and increasing her chances of surgery.
- Chemotherapy: Six months of FOLFIRINOX treatment.
- Radiation: Five days of stereotactic body radiation therapy (SBRT).
Following her rigorous treatment, a scan revealed that the tumor had shrunk, making her eligible for surgery.
Successful Surgery and Recovery
On September 30, 2014, Connie underwent surgery at Johns Hopkins, where Dr. John Cameron opted for a distal pancreatectomy and splenectomy instead of the initially planned Whipple procedure. This decision underscored the success of her prior treatments, offering her a new lease on life.
Managing Life After Treatment
Post-surgery, Connie faced the challenges of recovery, including fatigue, hair loss, and appetite changes. With the help of palliative care, she found relief from these side effects. Under the guidance of Dr. Chirag Patel at the Cleveland Clinic, she learned to manage her symptoms effectively.
To maintain her strength, Connie engaged in regular exercise, incorporating walking and weightlifting into her routine. Additionally, she experimented with supplements and complementary therapies, such as light therapy and acupressure.
The Importance of Genomic Testing
As part of her treatment journey, Connie underwent genomic testing through FoundationOne, which revealed an MSH6 mutation and a diagnosis of Lynch syndrome. This genetic condition heightened her risk for various cancers, necessitating vigilant surveillance for related health issues.
Embracing Life Fully
Today, Connie leads an active life, having adjusted her work schedule to part-time to enjoy travel and family celebrations. Her energy levels have stabilized, and she exercises regularly, refusing to let her past define her future.
In a heartfelt tribute, we remember that six years after her diagnosis, Connie passed away, leaving behind a legacy of strength and inspiration for others facing similar battles. Her story serves as a vital reminder of the importance of genetic testing in navigating cancer treatment and the potential for life beyond diagnosis.
