Embracing Resilience: Why Failure is Never an Option for Success

Christine Shaffer’s Inspiring Battle Against Pancreatic Cancer
At 67 years old, Christine Shaffer’s life took a drastic turn when she was diagnosed with pancreatic cancer in 2017. What began as persistent lower back pain led to a shocking discovery: a tumor on her pancreas. Despite the challenges and the grim statistics surrounding this aggressive disease, Christine’s story is one of resilience and unwavering determination.
A Tumultuous Diagnosis
Initially, Christine’s symptoms were misdiagnosed as a urinary tract infection. However, after a CT scan revealed a 2.7 x 2.8 cm tumor near the tail of her pancreas, her healthcare journey took a critical turn. With no visible metastases or lymph node involvement, she sought treatment at the renowned Moffitt Cancer Center in Tampa, Florida.
- Initial treatment plan: Chemotherapy, radiation, and surgery.
- Tumor type: No metastasis detected.
Facing Treatment Head-On
Under the guidance of the Tumor Board at Moffitt, Christine underwent a rigorous neoadjuvant treatment regimen that included FOLFIRINOX, a chemotherapy combination known for its intensity. Despite the debilitating side effects, including significant weight loss and dehydration, Christine pushed through, supported by her husband, a biomedical engineering enthusiast.
- Weight loss: 35 pounds.
- Emergency visits: Four due to dehydration.
Her husband’s relentless research led them to Dr. Theodore Hong at Mass General in Boston, who was studying the effects of losartan, a blood pressure medication, alongside chemotherapy. This combination resulted in a remarkable 55% reduction in the tumor’s size.
Surgery and Recovery
After successful chemotherapy, Christine progressed to stereotactic body radiation treatment (SBRT), which further reduced the tumor to a mere 25% of its original size. This positive response paved the way for surgery, where two-thirds of her pancreas was successfully removed by Dr. Pamela Hodul at Moffitt.
- Surgery details: Two-thirds of pancreas removed; spleen also taken out.
- Post-surgery treatment: Three cycles of Gemzar to eliminate any residual cancer cells.
Today, Christine continues her journey with Dr. William McGarry in Vero Beach, Florida, enjoying a life free from diabetes and the need for digestive enzymes.
Facing New Challenges
Despite the initial success, Christine faced a setback in August 2018 when her CA 19-9 levels spiked and her previously stable pulmonary nodules began to grow. The medical team decided to monitor the situation closely, opting for a cautious approach.
- CA 19-9 level: Increased to 486.
- Next steps: Consultation with Dr. Frank Kaszuba, a pulmonary oncologist, for potential biopsy.
The Power of Faith and Advocacy
Christine attributes her perseverance to a revitalized faith in God, which sustained her through the toughest times. She emphasizes the importance of having a strong support system and advocates for individuals facing similar diagnoses to seek out knowledgeable doctors and stay informed about the latest treatments.
- Key to success: Faith and proactive medical advocacy.
Christine’s journey is a testament to courage, hope, and the relentless pursuit of treatment options in the face of a challenging diagnosis. While she tragically passed away in September 2019, her legacy continues to inspire others in the fight against pancreatic cancer. Her story highlights the critical need for research, support, and advocacy in battling this aggressive disease.