How My Vigilance Led to Early Detection of Pancreatic Cancer: A Life-Saving Journey

Beverly Leighton’s journey with pancreatic cancer is a powerful testament to the importance of early detection and genetic testing. Having witnessed the devastating effects of this disease in her family, she took proactive steps that ultimately led to her early diagnosis and successful treatment. Here’s a closer look at her experience and the lessons learned along the way.

A Family Legacy of Pancreatic Cancer

Beverly’s connection to pancreatic cancer dates back to her childhood. At just 10 years old, she lost her grandfather to this aggressive disease. Years later, in April 1998, tragedy struck again when her mother was diagnosed with pancreatic cancer and passed away just months later at the age of 62. Through her research, Beverly discovered a troubling pattern that suggested a genetic predisposition to this illness, highlighting the importance of understanding family medical history.

The Impact of Research and Awareness

When Beverly’s mother faced her battle with cancer, reliable information was scarce. The internet was still in its infancy, and resources were limited. However, she was able to connect with the National Familial Pancreas Tumor Registry at Johns Hopkins University. Through their newsletters and updates, she learned about the evolving landscape of pancreatic cancer research and began to advocate for herself and her family.

Taking Charge with Early Screening

In 2017, Beverly received a newsletter detailing the CAPS5 study, which focused on early detection methods for pancreatic cancer. Eager to participate, she engaged in annual screenings through advanced techniques like endoscopic ultrasound (EUS) and MRI. In April 2019, during one such screening, her gastroenterologist, Dr. Amitabh Chak, discovered a suspicious mass on the tail of her pancreas. Despite having no symptoms, Beverly was diagnosed with a 1 cm adenocarcinoma, an early-stage cancer that is rarely detected so promptly.

Undergoing Surgery and Chemotherapy

Beverly’s journey continued with a successful distal pancreatectomy and splenectomy on April 26, 2019. This laparoscopic procedure lasted over nine hours, and she was discharged just a few days later. Alongside her surgery, she underwent genetic testing, which revealed the FAMMM genetic mutation. Following her surgery, she participated in adjuvant chemotherapy, receiving 12 rounds of FOLFIRINOX treatment. Although she faced challenges like hair loss and fatigue, she remained resilient and committed to her recovery.

Monitoring Progress and Staying Vigilant

Since her surgery, Beverly has consistently monitored her health. She has undergone multiple CT scans and a PET scan, with all results indicating no evidence of disease (NED). Her CA 19-9 marker levels have also shown promising signs, reflecting her successful treatment. Her oncologist emphasizes the importance of ongoing surveillance, scheduling routine scans and bloodwork to ensure her health remains stable.

The Importance of Genetic Testing and Family Support

Beverly acknowledges the fear that accompanies a pancreatic cancer diagnosis, especially given her family history. However, her proactive approach to genetic testing and early screening has given her a sense of control. Her daughters, especially the eldest, have begun to engage in testing as well, reducing the anxiety of potential hereditary risks. Support from her family has been invaluable throughout her journey, providing emotional strength and encouragement.

In conclusion, Beverly Leighton’s story serves as a powerful reminder of the critical role that early detection, genetic awareness, and family support play in battling pancreatic cancer. Her experience underscores the need for individuals with a family history of this disease to consider regular screenings and genetic counseling as vital steps towards safeguarding their health.