Navigating Life with Pancreatic Cancer: Insights and Opportunities in Clinical Trials

Rob Babcock’s Inspiring Journey Through Pancreatic Cancer

At 66 years old, Rob Babcock, a former basketball coach and NBA executive, faced a life-altering diagnosis that would challenge his resilience. In August 2017, while enjoying breakfast, Rob’s wife, a nurse, noticed a yellow tint in his eyes. This seemingly minor observation led to a series of medical tests that unveiled a mass on his pancreas, signaling the onset of pancreatic cancer. Despite the daunting diagnosis, Rob’s journey exemplifies hope, strength, and the importance of support and perseverance.

From Diagnosis to Treatment: The Path Ahead

• Initial Diagnosis: Jaundice prompted immediate medical attention.
• Clinical Trial Participation: Rob enrolled in a clinical trial for chemotherapy to shrink the tumor.
• Surgical Intervention: He underwent Whipple surgery followed by additional treatments.
• Recurrence: After a period of optimism, the cancer returned, leading to another clinical trial.

Upon learning about his diagnosis, Rob quickly sought medical help. His physician, Jana Marganian, arranged for a CT scan, which revealed that a mass was compressing his bile duct, causing the jaundice. A subsequent biopsy confirmed the presence of cancer, but fortunately, it was detected early, making intervention possible.

Choosing the Right Course of Treatment

Following consultation with several specialists, Rob learned that his tumor was "borderline resectable." He found hope through Dr. Howard Safran, who was conducting a clinical trial at the Lifespan Cancer Institute in Rhode Island, utilizing a chemotherapy regimen known as FOLFOX-A.

Rob embarked on this treatment, which consisted of ten infusions delivered biweekly. Remarkably, he maintained a rigorous workout routine throughout his treatment, managing only mild neuropathy in his extremities. Genomic testing revealed he lacked a genetic predisposition for pancreatic cancer, further bolstering his resolve.

After completing chemotherapy, Rob underwent five days of proton radiation therapy at Mass General in Boston, combined with additional chemotherapy. His proactive approach extended to selecting one of the country’s top surgeons, Dr. Carlos Fernandez del Castillo, for his upcoming surgery.

Surgery and Recovery: A New Chapter

On March 7, 2018, Rob underwent Whipple surgery, which proved successful, with clear margins found during the procedure. Out of 15 lymph nodes removed, only two showed cancer presence, prompting him to begin a new chemotherapy course with Gemzar.

The initial scans post-surgery were promising, but in October 2018, tests indicated a return of the cancer. Despite this setback, Rob prepared to enter an immunotherapy trial using durvalumab and MEDI5083, determined to face each challenge with a positive outlook.

Reflections on Life with Cancer

While receiving treatment, Rob observed the diverse backgrounds of fellow patients, many of whom faced their battles alone. He felt fortunate to have a robust support network, including his wife, children, and his beloved therapy cat, Rebound.

Rob’s experience has shaped his perspective on life, emphasizing the importance of a positive support system and proactive health management. He shared valuable insights for others navigating similar journeys, including:

• Health Maintenance: Prioritize overall well-being to enhance resilience against illnesses.
• Nutrition Matters: Focus on a healthy diet, minimizing sugar and processed foods.
• Stay Active: Physical fitness plays a crucial role in recovery and treatment tolerance.
• Research and Advocate: Be assertive in medical discussions and seek second opinions when needed.
• Mental Well-Being: Engage in stress-reducing activities such as yoga or meditation.

Rob’s journey through pancreatic cancer has been one of strength and learning. He encourages others to appreciate every moment and relationship. His story serves as a reminder that even in adversity, love, support, and a fighting spirit can lead to hope and inspiration.

A Legacy of Strength

Rob’s commitment to clinical trials not only aided his own journey but also contributed valuable insights for future patients battling pancreatic cancer. Though he faced challenges, his legacy continues to inspire those navigating similar paths.

Every day is a gift, and Rob’s unwavering spirit reminds us all to cherish the love and support we receive from our families and friends. His journey may have ended, but his story lives on, encouraging others to fight against the odds.